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Point Of Care Testing (POCT) and  Advantages

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Point of care testing

Healthcare providers strive to treat patients as rapidly as possible while achieving the greatest potential outcome. Quick and accurate test results can assist health practitioners to deliver the best possible Point Of Care Testing to their patients by allowing them to make better and more effective decisions.

Point of care testing, also defined as near-patient testing, is performing a test in the presence of the researcher with a device or test kit rather than sending a sample to a laboratory. Many innovative point-of-care gadgets make use of technological advancements to keep improving care quality.

 

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What is point-of-care testing?

The sufferer location is referred to as point click care login in this application. If all samples and specimens are sent to medical laboratories for processing, the findings will take a long time to get back. This might result in time being spent in important situations or patients being treated without their treatment team having all of the information they require.

Instead, POC testing makes it much easier to get accurate and timely findings. Medical professionals may make better-informed judgments about a patient’s treatment and care now that these data are available.

Advantages and disadvantages of point-of-care testing vs. laboratory testing:

  • The key benefit of point-of-care testing is the speed with which a result may be obtained. Results are usually given in an easy-to-understand format, although this is not always the case, and results may still need to be safely interpreted by a healthcare expert.
  • People who have not undergone professional laboratory training can also undertake POC testing. This involves the use of nurses, physicians, and paramedics, as well as patient testing. Malaria antigen screening, pregnancy tests, glycaemic control, urinalysis, and other types of near-patient testing are only a few examples.
  • These tests frequently need the collection of simple samples such as bodily fluids (such as saliva or urine) or blood via a finger prick. They can be used in conjunction with other portable medical devices, such as thermometers or blood pressure monitors, to provide a quick and easy medical examination.
  • POC testing, on the other hand, has several drawbacks. Studies have revealed that mistakes are more likely with POC testing than with laboratory analysis, based on the available technology in the device. This can occur because the POC testing environment is less regulated than laboratory circumstances, and the findings are more susceptible to external interference than laboratory operations, resulting in inaccuracy.
  • POC testing can potentially be more expensive than lab-based testing. According to 1995 research, the cost of POC glucose testing was 1.1 to 4.6 times greater than the cost of the same test in the lab. Hidden expenses, such as those connected with a quality control program or equipment care, are sometimes neglected. Other types of hidden expenses, such as facilities, personnel, and overheads, might also apply to laboratory testing.
  • Nonetheless, the simplicity and immediacy of POC testing can offset the higher expenses. Rapid findings allow a treatment plan to be implemented swiftly, which may make a great difference when time is of the essence for improved care.
  • These tests frequently need the collection of simple samples such as bodily fluids (such as saliva or urine) or blood via a finger prick. They can be used in conjunction with other portable medical devices, such as thermometers or blood pressure monitors, to provide a quick and easy medical examination.
  • POC testing, on the other hand, has several drawbacks. Studies have revealed that mistakes are more likely with POC testing than with laboratory analysis, based on the available technologies in the equipment. This can occur because the POC clinical laboratory and att net email login are less regulated than laboratory circumstances, and the findings are more susceptible to external interference than laboratory operations, resulting in inaccuracy.
  • POC testing can potentially be more expensive than lab-based testing. According to 1995 research, the cost of POC glucose testing was 1.1 to 4.6 times greater than the cost of the same test in the lab. Hidden expenses, such as those connected with a quality control program or equipment care, are sometimes neglected. Other types of hidden expenses, such as facilities, personnel, and overheads, might also apply to laboratory testing.
  • Nonetheless, the simplicity and immediacy of POC testing can offset the higher expenses. Rapid findings allow a treatment plan to be implemented swiftly, which may make a great difference when time is of the essence for improved care.

Point-of-care hematology devices:

POC testing equipment can perform a variety of assays, including complete blood counts:

  1. Blood clots are assessed with prothrombin time analyzers.
  2. For hemostatic evaluation, aPTT testing is used.
  3. To rule out a blood clot or DVT, D-dimer testing is used.
  4. The viscoelastic assay was performed, for trauma and obstetrics.
  5. Heparin levels are monitored via activated clotting time testing.
  6. Malaria antigen testing is used to check for the disease.

The most widely used and current point-of-care testing instruments have been proved to deliver accurate and trustworthy hematological findings, resulting in enhanced medical care for a variety of illnesses.

Past and Present Point-of-Care Testing:

Donchez and Avery reported in 1917 that pneumococcal polysaccharides may be identified by immunoassay of serum and urine from patients with lobar pneumonia, which may have been the first large-scale application of the immunoassay for infectious illness diagnosis (1). The authors made a foresightful observation when they indicated that antigen detection may help with infection diagnosis. The great sensitivity is given by the radioimmunoassay (RIA) in 1960. And the enzyme-linked immunoassay (ELISA) in 1971 sparked interest in immunoassays for antigen or antibody for disease diagnosis.

In the non-POC central laboratory scenario, the ELISA remains the leading immunoassay platform technology. ELISA technique also allows for high-throughput specimen preparation thanks to automation. The ELISA and RIA platforms, on the other hand, are time-consuming, have a medium to the high level of complexity that necessitates the use of qualified laboratory employees, and are often equipment-intensive. As a result, these technologies are not suitable for use in a POC.

The LFIA platform is used by the majority of POC fast diagnostics. The LFIA platform is incredibly adaptable. Antibodies to one analyte epitope are tagged with a reporting, such as au nanoparticles, and a capture antibody to a second epitope on the same analyte is immobilized on the lateral flow strip to detect high-molecular-weight antigens. The strength of the signal at the test line in an antigen-capture sandwich configuration is proportional to the concentration of the analyte. POC diagnostics for infectious disorders that detect microbial products in clinical samples, such as the group A streptococcal cell wall carbohydrate, are based on sandwich immunoassays. A competitive format is required for the determination of trace analytes using a single antigenic determinant.


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